Of those infected, 1,875 are already confirmed as having AIDS, it said.
It said the highest rate of HIV infection, 40.2 percent, was among the 25 to 34 age group, with most victims being men. Males accounted for 93.3 percent of all infected cases.
With testing facilities limited and HIV-infected people or those living with AIDS often unwilling to come forward, the health ministry estimates that Iran actually has 80,000 HIV cases — four times higher than the registered figure.
According to official ministry figures, however, at least 3,236 people have died in Iran after developing full-blown AIDS, although the report did not say when such deaths started being recorded.
The main cause of infection remained intravenous drug use, the report said, with 77.5 percent of people contracting the virus this way.
Infection through sexual contact accounted for 13.1 percent, while transmission from mother to baby accounted for 0.9 percent of the total infections.
The health ministry is concerned that sexual transmission of HIV could reach epidemic level because around 60 percent of the country's nearly 71-million population is under the age of 30 according to the 2006 national census, the news agency said.
Sexual relations outside marriage are banned in the Islamic republic.
