Mottaki arrived in New Delhi earlier on Thursday.
He is due to meet Indian Prime Minister Manmohan Singh later in the day.
During his two-day visit, Mottaki will also hold meetings with the ministers of foreign affairs and oil, Pranab Mukherjee and Murli Deora respectively.
The state-run news agency ISNA reported on Wednesday that discussions during his visit will focus on regional and international issues of concern, and trade deals including a proposed gas pipeline stretching through Pakistan.