Al-Assad will meet and hold talks with senior Iranian officials.
The main aim of the trip is to strengthen Tehran-Damascus bilateral relations in the wake of pressure exerted by the United States, the government-run news agency Mehr said.
Arabic press reports have said that al-Assad will hold talks with Irans Supreme Leader Ayatollah Ali Khamenei and President Mahmoud Ahmadinejad.
Syrian Foreign Minister Walid al-Mu’allem will accompany him.
Regional allies Iran and Syria are both accused by the United States of being state sponsors of terrorism.
